Multiplexed Tissue Imaging to Reveal the Spatial Biology of CancerClick to enlarge
During this presentation of the Cancer Moonshot Seminar Series, Sandro Santagata, M.D., Ph.D. (Brigham and Women’s Hospital) discusses multiplexed tissue imaging to reveal the spatial biology of tumors. This work is related to the Blue Ribbon Panel recommendation to generate human tumor atlases.
Atlas Introduction with Dr. Sandro Santagata and Sarah ArenaClick to enlarge
This interview with Sandro Santagata, MD PhD, and Sarah Arena, MLIS, dive into the vision for the Gray BRCA Pre-Cancer Atlas.
Developing a Cloud Data Resource to Accelerate TB ResearchClick to enlarge
Bree Aldridge, PhD, Associate Professor at Tufts University School of Medicine and Tufts University School of Engineering, introduces the Tuberculosis Tumor Atlas.
Breast Cancer Atlas with Dr. Joan BruggeClick to enlarge
This interview with Dr. Joan Brugge describes her breast cancer research collected as part of the Gray BRCA Pre-Cancer Atlas.
Ovarian Cancer Atlas with Dr. Ronny Drapkin and Dr. Tanjina KaderClick to enlarge
This interview with Drs. Ronny Drapkin and Tanjina Kader describes preliminary ovarian cancer research collected as part of the Gray BRCA Pre-Cancer Atlas.
AACR Virtual Journal Club: Cancer Discovery With Dr. Peter SorgerClick to enlarge
This AACR Journal Club discusses features Peter Sorger, PhD, discussing his article “The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution.” The intricacies of primary melanoma progression are revealed by a combination of high-plex imaging, 3D high-resolution microscopy, and spatially resolved microregion transcriptomics. Dr. Sorger shows that this unprecedented spatiotemoporal resolution uncovers recurrent cellular neighborhoods and the landscape of immune evasion and immunoediting.
Profiling of the Tumor Microenvironment to Improve Diagnosis and TherapyClick to enlarge
This webinar presents two projects from the Ludwig Centers at Harvard and MIT that are part of the Ludwig Tumor Atlas Project. The Ludwig Tumor Atlas applies diverse technologies to probe the tumor environment using a variety of methods, including highly multiplexed tissue imaging, dissociative single cell sequencing, spatial transcriptomics and conventional histology.
Multiplexed Technologies for Spatial Analysis of FFPE Tumor SamplesClick to enlarge
Zoltan Maliga, PhD, Scientific Director of Tissue Imaging at the Laboratory of Systems Pharmacology, describes using multiplexed fluorescent tissue imaging to characterize Formalin-Fixed Paraffin-Embedded (FFPE) tissues.